Ipratropium Bromide Impurity 13(Ipratropium EP Impurity E)
endo-(±)-8-aza-8-isopropylbicyclo[3.2.1]oct-3-yl (hydroxymethyl)phenylacetate
CAS: 22235-81-0
Molecular Formula: C19H27NO3
Ipratropium Bromide Impurity 13(Ipratropium EP Impurity E) - Names and Identifiers
Ipratropium Bromide Impurity 13(Ipratropium EP Impurity E) - Physico-chemical Properties
| Molecular Formula | C19H27NO3 |
| Molar Mass | 317.42258 |
| Density | 1.15±0.1 g/cm3(Predicted) |
| Melting Point | 112-114°C |
| Boling Point | 448.8±45.0 °C(Predicted) |
| Solubility | Chloroform (Slightly), Methanol (Slightly) |
| Appearance | Solid |
| Color | White to Pale Orange |
| pKa | 14.12±0.10(Predicted) |
| Storage Condition | Refrigerator |
Ipratropium Bromide Impurity 13(Ipratropium EP Impurity E) - Upstream Downstream Industry
| Raw Materials | Noratropine endo-8-isopropyl-8-azabicyclo[3.2.1]octan-3-ol Acetyltropylic chloride Ethyl phenylacetate Atropine Acetone |
Ipratropium Bromide Impurity 13(Ipratropium EP Impurity E) - Introduction
endo-(±)-8-aza-8-isopropylbicyclo[3.2.1]oct-3-yl is an organic compound with the chemical name endo-(±)-8-aza-8-isopropylbicyclo[3.2.1]oct-3-yl.
Nature:
endo-(±)-8-aza-8-isopropylbicyclo[3.2.1]oct-3-yl is a white crystalline solid, insoluble in water at room temperature, soluble in some organic solvents such as ethanol and Ether solvents. Its structure contains eight-membered heterocyclic ring, in which the nitrogen atom and the hydroxy methyl group on the benzene ring make it have special chemical properties.
Use:
endo-(±)-8-aza-8-isopropylbicyclo[3.2.1]oct-3-yl is mainly used in the field of drug research and manufacturing. It is an impurity of the peripheral anticholinergic drug ipratropium bromide. It is used to detect the purity and quality of ipratropium bromide products and perform quality control.
Method:
endo-(±)-8-aza-8-isopropylbicyclo[3.2.1] The preparation method of oct-3-yl (hydroxymethyl)phenylacetate is generally realized by organic synthetic chemical reaction. Specific methods include the synthesis of intermediate compounds followed by specific reaction steps to give the final product.
Safety Information:
Nature:
endo-(±)-8-aza-8-isopropylbicyclo[3.2.1]oct-3-yl is a white crystalline solid, insoluble in water at room temperature, soluble in some organic solvents such as ethanol and Ether solvents. Its structure contains eight-membered heterocyclic ring, in which the nitrogen atom and the hydroxy methyl group on the benzene ring make it have special chemical properties.
Use:
endo-(±)-8-aza-8-isopropylbicyclo[3.2.1]oct-3-yl is mainly used in the field of drug research and manufacturing. It is an impurity of the peripheral anticholinergic drug ipratropium bromide. It is used to detect the purity and quality of ipratropium bromide products and perform quality control.
Method:
endo-(±)-8-aza-8-isopropylbicyclo[3.2.1] The preparation method of oct-3-yl (hydroxymethyl)phenylacetate is generally realized by organic synthetic chemical reaction. Specific methods include the synthesis of intermediate compounds followed by specific reaction steps to give the final product.
Safety Information:
Last Update：2024-04-09 02:00:51
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Product Name: N-Isopropylnoratropine (NINA) Visit Supplier Webpage Request for quotationCAS: 22235-81-0
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Spot supply
Product Name: N-Isopropylnoratropine Visit Supplier Webpage Request for quotationCAS: 22235-81-0
Tel: +86-400-900-4166
Email: product@acmec-e.com
Mobile: +86-18621343501
QQ: 2881950922
Wechat: 18621343501
WhatsApp: +86-18621343501
Spot supply
Product Name: N-Isopropylnoratropine (NINA) Visit Supplier Webpage Request for quotationCAS: 22235-81-0
Tel: +86-18821248368
Email: Int06@meryer.com
Mobile: +86-18821248368
QQ: 495145328
WhatsApp: +86-18821248368
View History
Ipratropium Bromide Impurity 13(Ipratropium EP Impurity E)
2-[(2-FORMAMIDO-4-METHYLSULFANYLBUTANOYL)AMINO]PROPANOIC ACID
TOSLAB 719797
ETHYL 2-FORMYLPROPIONATE
LABOTEST-BB LT00455578
(1R,2R)-1-氨基-2-(二氟甲基)-N-[(1-甲基环丙基)磺酰基]环丙烷甲酰胺盐酸盐
TOSLAB 798547
TRIMETHYLPHOSPHINE-SILVER IODIDE COMPLEX
[2 - (6 - 氨基-嘌呤-9 - 基) - 1 - 甲基 - 乙氧基甲基]膦酸甲氧羰基氧甲基酯异丙氧基羰基氧基甲基酯
3-氨基哌啶-2,6-二酮盐酸盐 或者是三氟乙酸盐
2-[(2-FORMAMIDO-4-METHYLSULFANYLBUTANOYL)AMINO]PROPANOIC ACID
TOSLAB 719797
ETHYL 2-FORMYLPROPIONATE
LABOTEST-BB LT00455578
(1R,2R)-1-氨基-2-(二氟甲基)-N-[(1-甲基环丙基)磺酰基]环丙烷甲酰胺盐酸盐
TOSLAB 798547
TRIMETHYLPHOSPHINE-SILVER IODIDE COMPLEX
[2 - (6 - 氨基-嘌呤-9 - 基) - 1 - 甲基 - 乙氧基甲基]膦酸甲氧羰基氧甲基酯异丙氧基羰基氧基甲基酯
3-氨基哌啶-2,6-二酮盐酸盐 或者是三氟乙酸盐
Raw Materials for Ipratropium Bromide Impurity 13(Ipratropium EP Impurity E)
Noratropine
endo-8-isopropyl-8-azabicyclo[3.2.1]octan-3-ol
Acetyltropylic chloride
Ethyl phenylacetate
Atropine
Acetone
endo-8-isopropyl-8-azabicyclo[3.2.1]octan-3-ol
Acetyltropylic chloride
Ethyl phenylacetate
Atropine
Acetone